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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC1L
All Species:
38.79
Human Site:
Y580
Identified Species:
71.11
UniProt:
Q13415
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13415
NP_004144.2
861
97350
Y580
L
T
E
P
H
Q
V
Y
V
Q
I
L
Q
K
L
Chimpanzee
Pan troglodytes
XP_513408
861
97367
Y580
L
T
E
P
H
Q
V
Y
V
Q
I
L
Q
K
L
Rhesus Macaque
Macaca mulatta
XP_001111614
860
97440
Y579
L
T
E
P
H
Q
V
Y
V
Q
I
L
Q
K
L
Dog
Lupus familis
XP_532575
858
97161
Y578
L
T
E
P
H
Q
V
Y
V
Q
I
L
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N2
840
95057
Y559
L
T
E
P
H
Q
V
Y
V
Q
I
L
K
K
L
Rat
Rattus norvegicus
Q80Z32
848
95741
Y567
L
T
E
P
H
Q
V
Y
V
Q
I
L
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026457
858
96850
Y578
L
T
D
P
H
Q
A
Y
V
Q
I
L
E
L
L
Frog
Xenopus laevis
NP_001081806
886
99953
Y606
L
T
D
P
H
Q
A
Y
V
Q
I
L
K
L
L
Zebra Danio
Brachydanio rerio
NP_956227
910
101179
Y629
M
T
D
P
H
Q
A
Y
V
Q
I
L
Q
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16810
924
103263
Y644
L
T
E
P
R
Q
A
Y
V
Q
I
Y
K
Q
L
Honey Bee
Apis mellifera
XP_392056
490
55682
Q219
A
Y
V
Q
I
L
K
Q
L
Y
N
K
T
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798977
905
100707
T622
A
Q
V
D
A
A
V
T
E
M
F
C
S
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567440
809
91877
L533
W
K
K
A
L
Q
S
L
N
E
R
F
A
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
81.5
N.A.
66
69.8
N.A.
N.A.
50.5
52.4
48.6
N.A.
33.4
31.8
N.A.
29.7
Protein Similarity:
100
98.9
97.3
88.8
N.A.
77.9
79.9
N.A.
N.A.
66.3
67
63.1
N.A.
52.7
43.5
N.A.
47.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
73.3
73.3
80
N.A.
66.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
93.3
N.A.
80
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
8
8
31
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
24
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
54
0
0
0
0
0
8
8
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
77
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
8
0
0
0
0
8
24
54
8
% K
% Leu:
70
0
0
0
8
8
0
8
8
0
0
70
0
16
77
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
77
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
8
0
85
0
8
0
77
0
0
47
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% S
% Thr:
0
77
0
0
0
0
0
8
0
0
0
0
8
0
8
% T
% Val:
0
0
16
0
0
0
54
0
77
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
77
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _